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Adult: 500 mg every 12 hours or 250 mg every 8 hours; Children: 25 mg/kg/day in divided doses every 12 hours or 20 mg/kg/day in divided doses every 8 hours; Ear/Nose/Throat Infection (Severe): Adult: 875 mg every 12 hours or 500 mg every 8 hours; Children: 45 mg/kg/day in divided doses every 12 hours or 40 mg/kg/day in divided doses every 8 hours . spironolactone 25 mg obat untuk apa